All therapies
BCMA-directed Developed & approved in China Published paper

Equ-cel

Equecabtagene autoleucel · sold in China as FUCASO

A CAR T-cell therapy for multiple myeloma that has come back or stopped responding to other treatment. Made from your own immune cells, delivered at SinoUnited Health in Shanghai.

See the full treatment journey
What it is

A therapy made from your own cells.

A plain-language look at what Equ-cel is and how it works — general to this class of therapy, not specific to any one patient's result.

Equecabtagene autoleucel — Equ-cel for short — is a type of CAR T-cell therapy. Your own T-cells (part of your immune system) are collected, then re-engineered to recognize a protein called BCMA that sits on the surface of myeloma cells. Once returned to your body, these modified cells seek out and destroy myeloma cells.

It is an autologous therapy, meaning it is made from your own cells rather than a donor's. Equ-cel is a BCMA-directed CAR T-cell therapy developed in China and approved by China's National Medical Products Administration (NMPA) for relapsed or refractory multiple myeloma.

Approved indication

NMPA-approved

Adult patients with relapsed or refractory multiple myeloma, who have demonstrated disease progression after at least three lines of prior treatment (at least one proteasome inhibitor and one immunomodulatory agent).

How it works

How Equ-cel is given.

Equ-cel follows the same CAR T-cell pathway as other therapies of its class — offered at SinoUnited as an all-inclusive “2+21” package across two trips to Shanghai, with the manufacturing weeks spent at home.

Diagram of the CAR T-cell process: blood is drawn, T-cells are re-engineered in the lab to express a CAR protein, grown in number, infused into the patient, and the CAR T-cells bind to and destroy cancer cells.
The CAR T-cell process, in five steps — from cell collection to the engineered cells binding the target antigen.
Stage 01

Collection

Blood and eligibility tests, then your T-cells are collected by apheresis — both done on-site at SinoUnited Health.

Trip one · ~1 week, Shanghai
Stage 02

Manufacturing

Your cells are engineered to target BCMA and expanded while you return home and wait.

3–4 weeks · at home
Stage 03

Lymphodepletion

A short course of chemotherapy prepares your body to receive the engineered cells.

Trip two · Shanghai
Stage 04

Infusion & recovery

Your Equ-cel is returned in a single infusion, followed by close inpatient monitoring.

Trip two · ~3 weeks, Shanghai

The full pathway at SinoUnited spans approximately two months across two trips to Shanghai, with the manufacturing period spent at home. See the patient journey for the detail.

Who it's for

Where Equ-cel may be an option.

Eligibility is set honestly here as a general guide — the decision itself rests with a qualified physician who has reviewed your case.

Condition treated

Multiple myeloma

Read about multiple myeloma at SinoUnited
  • Adults whose multiple myeloma is relapsed or refractory — it has returned, or has not responded to previous treatment.
  • After three or more prior lines of therapy, including a proteasome inhibitor and an immunomodulatory agent.
  • A good level of general fitness (ECOG 0–1) is usually needed.

This information is a general guide only. Whether Equ-cel is right for you is a decision made by a qualified physician after reviewing your individual case.

What it treats

For multiple myeloma.

Equ-cel is directed at the B-cell maturation antigen (BCMA), expressed on the plasma cells that drive multiple myeloma.

BCMA-targeted

Multiple myeloma

Cancer of
Plasma cells, in the bone marrow
Incidence
Second most common blood cancer
Considered at
Relapsed / refractory disease

Multiple myeloma is a cancer of the plasma cells — the antibody-producing white blood cells in the bone marrow. It is not usually curable, but is treatable through successive lines of therapy that control the disease.

For disease that has relapsed or become refractory after exposure to standard immunomodulatory drugs and proteasome inhibitors, BCMA-directed CAR T-cell therapy is an established option targeting the B-cell maturation antigen expressed on plasma cells.

Multiple myeloma details
Safety & side effects

Managed with close monitoring.

Two blocks, kept deliberately separate: what is true of this class of therapy in general, and what SinoUnited provides.

General to CAR T-cell therapy

CRS and neurological effects

Like all CAR T-cell therapies, Equ-cel can cause side effects that need close monitoring. The two most discussed are cytokine release syndrome (CRS) — the immune system reacting as the therapy works — and neurological effects (ICANS). Most cases are manageable when caught early, which is why treatment is delivered as an inpatient stay with continuous monitoring.

At SinoUnited Health

Supervised, with intensive care on hand

SinoUnited Health provides infusion and recovery as a supervised inpatient stay, with on-site intensive care available if escalation is ever needed.

Tocilizumab, the standard treatment for severe cytokine release syndrome, is available on site.

5on-site ICUs
Published evidence

A therapy our clinical lead has published on.

SinoUnited's CAR-T program has Dr. Lily Zhou, M.D., Ph.D., Chief of Hematology, with a postdoctoral fellowship at UCSF and 25 publications indexed in PubMed. Dr. Zhou co-authored a 2025 peer-reviewed case report in Frontiers in Immunology on BCMA CAR-T treatment — the same class of therapy as Equ-cel.

Reference BCMA-directed CAR T-cell therapy case report. Frontiers in Immunology, 2025. DOI 10.3389/fimmu.2025.1567403 → · PMID 40491928.

A case report describes the course of a single patient. It is evidence that SinoUnited's clinical lead is published in this field — it is not, and must not be read as, an indication of outcomes across patients. Outcomes vary and are determined by individual circumstances.

Meet Dr. Zhou
Dr. Lily Zhou, Chief of Hematology at SinoUnited Health, in a white clinical coat.
Dr. Lily Zhou, M.D., Ph.D. Chief of Hematology
Cost

One all-inclusive package.

2 + 21days, across two stays

SinoUnited offers CAR-T as an all-inclusive “2+21” package — covering the collection stay and the three-week infusion stay. The full breakdown of what's included, and pricing, lives on the Costs page as a single source of truth.

Questions

Common questions.

Is Equ-cel available in my country?

It is delivered at SinoUnited Health in Shanghai. Both collection and infusion are done on-site — they cannot be carried out in your home country.

How long does the whole process take?

About two months across two trips to Shanghai, with the four-to-six-week manufacturing period spent at home in between.

What does it cost?

CAR-T is offered as one all-inclusive “2+21” package. The full cost breakdown is set out on the Costs page.

What are the side effects?

The most discussed are cytokine release syndrome (CRS) and neurological effects (ICANS), which is why treatment is delivered as a monitored inpatient stay. SinoUnited-specific detail will be added once confirmed by Dr. Zhou.

Can my myeloma doctor at home stay involved?

Yes. SinoUnited coordinates follow-up with your local physicians, with three-monthly reviews recommended after treatment.

Eligibility

Not sure if Equ-cel is an option?

Start a remote assessment before you travel. It asks only for basic contact details and your diagnosis — your records are then reviewed by Dr. Zhou's hematology team.